Amneal Launches FOCINVEZ™, the First Ready-to-Use Version of Fosaprepitant

July 9, 2024
  • FOCINVEZ (fosaprepitant) 150 mg/50 mL single dose vial is an anti-nausea agent for highly emetogenic and moderately emetogenic chemotherapy (HEC and MEC)
  • Second injectable RTU product launched by Amneal in 2024

Amneal Pharmaceuticals, Inc. (NASDAQ: AMRX) (“Amneal” or the “Company”) and Steriscience today announced the launch of FOCINVEZ™, a ready-to-use injectable. Unlike other versions of fosaprepitant, this single-dose vial product is free of Polysorbate 80 and does not require reconstitution or dilution and can be administered directly from the vial using the included vial hanger. The product has been in-licensed from and is manufactured by Steriscience, a global sterile injectables company, and developed by SPES Pharmaceuticals, a specialized R&D firm that focuses on creating proprietary new formulations.

FOCINVEZ for injection is indicated in adults and pediatric patients 6 months of age and older, in combination with other antiemetic agents, for the prevention of: acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy (HEC), including high-dose cisplatin, and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy (MEC).

“We continue to launch differentiated complex products that are clinically impactful,” said Sean McGowan, Vice President, Biosimilars and Branded Oncology. “This is the second ready-to-use injectable we have launched this year that offers hospitals and oncology clinics a new presentation format that can improve pharmacy efficiency. These new 505(b)(2) injectables represent a new vector of growth for our expanding injectables portfolio.”

FOCINVEZ has a unique J-Code from the Centers for Medicare & Medicaid Services (CMS) to facilitate reimbursement: J1434, Injection, fosaprepitant (focinvez), 1 mg, and is available in one vial size 150mg/50mL (3mg/mL).

Adverse effects reported with FOCINVEZ include fatigue, diarrhea, neutropenia, asthenia, anemia, peripheral neuropathy, leukopenia, dyspepsia, urinary tract infection, and pain in extremity. For full prescribing information, see package insert located here.

According to IQVIA®, U.S. annual sales for fosaprepitant for the 12 months ended April 2024 were approximately $36 million.

About Amneal

Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX), headquartered in Bridgewater, NJ, is a global pharmaceutical company. We make healthy possible through the development, manufacturing, and distribution of a diverse portfolio of over 280 pharmaceutical products, primarily within the United States. In its Generics segment, the Company is expanding across a broad range of complex product categories and therapeutic areas, including injectables and biosimilars. In its Specialty segment, Amneal has a growing portfolio of branded pharmaceuticals focused primarily on central nervous system and endocrine disorders, with a pipeline focused on unmet needs. Through its AvKARE segment, the Company is a distributor of pharmaceuticals and other products for the U.S. federal government, retail, and institutional markets. For more information, please visit

About Steriscience

Headquartered at Bengaluru, India, Steriscience is a global sterile injectable company that focuses on bringing first-to-market value added offerings to solve the rising needs of healthcare professionals and patients across the globe. With a product portfolio designed to increase patient access and ensure supply security for critical sterile pharmaceuticals, Steriscience strives to improve convenience and compliance across the hospital value chain by developing and supplying high-quality medication globally.

About SPES Pharmaceuticals

Established in 2017 in North Brunswick, New Jersey, SPES Pharmaceuticals develops products with clinical advantages and improved safety profiles using proprietary technology platforms with a key focus on oncology, anti-emesis, CNS and pain management.

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Source: Amneal Pharmaceuticals, Inc.